Vyepti®

Break free from the cycle of migraine days.

Vyepti® Therapy for Chronic Migraines

Living with frequent or severe migraines can interrupt every part of your life—work, family time, and the moments that matter most. If other treatments haven’t provided lasting relief, Vyepti® offers an FDA‑approved option designed to help prevent migraines before they begin. Our experienced team delivers care in a comfortable, supportive environment focused on helping you take back control of your days, with evening and weekend appointment options to fit even the busiest schedule.

This innovative treatment, paired with our compassionate approach, can open the door to fewer migraine days and a better quality of life. Real relief is within reach.

Why Patients Choose Vyepti

Fewer Migraine Days
Clinical studies show Vyepti can significantly reduce the number of monthly migraine days for many patients.

Convenient Quarterly Treatment
Vyepti is given as an IV infusion once every 3 months, making it a simple preventive option without daily medication.

Rapid Onset of Effect
Because Vyepti is delivered directly into the bloodstream, many patients begin experiencing benefits as early as the first day after treatment.

About Vyepti®

What Makes Vyepti® Different?

1. Quarterly Treatment:

Most migraine preventives require a daily pill or monthly self-injections. VYEPTI® is given as an IV infusion once every 3 months in a clinic.

2. Proven Migraine Reduction:

Clinical studies show many patients experience a 50–75% reduction in migraine days, often sooner than with some daily preventive medications.

3. Consistent Protection:

Quarterly dosing provides continuous migraine prevention without needing daily medication or frequent injections.

How Vyepti® Works: The Science of Hope

1. Targets a Migraine Trigger:

VYEPTI® blocks CGRP, a protein that plays a key role in triggering migraines.

2. Prevents Migraines:

Rather than treating symptoms after a migraine begins, it helps prevent migraines from starting.

3. Fast Onset for Many Patients:

Some patients notice relief as early as the first day after infusion, while many oral preventives take weeks to work.

Who Can Benefit from Vyepti® Treatments

1. Adults With Migraines:

Approved for adults 18+ who want to prevent migraines before they start.

2. Patients Seeking Better Prevention:

Often used for people who have not found relief with traditional migraine

3. Insurance Requirements:

Many insurance plans require patients to try at least two other preventive treatments first.

What to Expect During Your Vyepti Infusion:

Treatment with Vyepti is simple and designed to fit comfortably into your schedule.

Consultation & Evaluation

Comfortable IV Infusion

Observation & Follow-Up

Treatment Details:

Targeted Migraine Prevention Designed for Real Life

  • Treatment Schedule: Once every 3 months
  • Administered by a healthcare provider in our clinic
  • Given through an IV infusion
  • Infusion time: 30 minutes for the infusion itself, but allow 60 minutes from arrival to departure

Are Migraines Holding You Back?

By reducing the monthly number of migraine days, Vyepti moves you forward.

Safety and Monitoring:

Is Vyepti® Right for You?

  • Adults 18 or older
  • Experience frequent migraines (episodic or chronic)
  • Have not found relief with traditional daily migraine medications
  • Want a preventive treatment to reduce how often and how severe migraines are

Managing Side Effects

One of the most promising aspects of Vyepti is its low side effect profile:

Common Side Effects
  • Stuffy nose
  • Scratchy throat
  • Mild reactions similar to seasonal allergies
Less Common Side Effects
  • High Blood Pressure  
  • Raynaud’s Phenomenon - heat and cold intolerance especially in hands and feet
  • These side effects are less common, but they can occur. Your healthcare provider will monitor your blood pressure and watch for signs of Raynaud’s, and will take action if necessary.

Why Choose HealthMates for Vyepti® Therapy:

Exceptional Environment

  • Spa-like atmosphere designed for comfort and relaxation
  • Flexible scheduling including evening and weekend hours
  • Compassionate care team dedicated to your improved well-being

Comprehensive Support

  • Insurance authorization assistance - we handle the paperwork
  • Co-pay assistance and reimbursement programs through Vyepti Connect – ask us for more information on this program
  • Coordinated care with your referring provider

Getting Started: A New Path to Fewer Migraine Days

Step 1: Enrollment

Complete our streamlined intake forms including in a brief health history, list of previously tried migraine medications, and insurance information. Cash payment options are also available.

Step 2: Consultation

Meet with a member of our care team who will assess your treatment history to determine if Vyepti is the right choice for you.

Step 3: Insurance Authorization

We handle all prior authorization paperwork with your insurance company, removing this common barrier to care.

Step 4: Pharmacy Coordination

Your medication is ordered through our specialty pharmacy partners and delivered directly to our office for your scheduled appointment.

Step 5: Treatment Begins

Start your Vyepti sessions in our comfortable, supportive environment with experienced medical supervision.

Step 6: Ongoing Care

In addition to your quarterly infusions, our team will conduct follow-up visits every four to six weeks to monitor your improvement. These monitoring appointments can be in person or via telehealth.

Frequently Asked Questions

Insurance and Payment Options?

Do I need a referral, or can I schedule myself?

How quickly will I see results?

Can I continue my other medications?

How long will I need treatment?

What if I’ve tried everything and nothing has worked?

Your Path to Migraine Relief Starts Here

Living with frequent or severe migraines can be exhausting, especially when you’ve tried multiple treatments without lasting relief. Vyepti® is an FDA-approved treatment designed to help prevent migraines before they start. In our comfortable, supportive setting, you’ll receive expert care from specialists who understand how deeply migraines can affect your daily life.

This innovative treatment, combined with our compassionate approach to care, can open the door to fewer migraine days and a better quality of life. Relief may be closer than you think.

Remember: seeking help is a sign of strength, not weakness. You deserve relief, hope, and the chance to feel like yourself again. We're here to support you every step of the way.